2 results listed
Erythromycin (Fig. 1)[1] is a bacteriostatic antibiotic macrolide produced by Streptomyces erythreus.
Erythromycin A is considered its major active component. Erythromycin can be used to treat bacteria responsible
for causing infections of the skin and upper respiratory tract, including Streptococcus, Staphylococcus,
Haemophilus and Corynebacterium genera. Nevertheless, the administration of erythromycin includes the
appearance of different side effects, such as diarrhea, nausea, abdominal pain, and vomiting, common, because
erythromycin is a motilin agonist [2]. Thus, the development of the methods of its efficient and rapid sensing is
really actual task.
International Symposium on Light Alloys and Composite Materials
UHAKS
Volodymyr V. Tkach
Marta V. Kushnir
Yana G. Ivanushko
Sílvio C. de Oliveira
Maryna M. Kornet
Mykhailo P. Zavhorodnii
Petro I. Yagodynets
The use of chemically modified electrodes (CME) is a very important step in electroanalytical chemistry [1].
Compared to the bare electrodes, they have some advantages, like:
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Rapidity;
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Low cost;
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Precisity;
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Exactity;
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Flexibility;
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Versatility in use;
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Affinity between the electrode modifier and the analyte.
On the other hand, quinone-hydroquinonic redox system is one of the most abundant in nature and, at the
same time, one of the most used as electrode modifiers in electroanalytical processes. For example, in [2],
tetrachloro-o-quinone is used as a modifier for sulphite electrochemical determination. Yet, in [3], the quinone-
hydroquinonic systems are present either in the electrode modifier or an analyte. It leeds to the possibility of use
of natural hydroquinonic compounds, like fumigatin, natural colorant and antibiotic, as electrode modifiers. For
now, no electroanalytical methods using fumigatin as electrode modifier have been developed. Nevertheless, from
its chemical composition, it is possible to suggest that it would be possible, so, in this work, this possibility is
theoretically analyzed.
The electroanalytical process, in the case of the typical two-proton – two-electron transference, may be
described as:
International Symposium on Light Alloys and Composite Materials
UHAKS
Volodymyr V. Tkach
Marta V. Kushnir
Petro I. Yagodynets