DRUG DESIGN WITH 3D PRINTER IN DIFFERENT ARCHITECTURES FOR DRUG DELIVERY SYSTEMS
Aleyna KUCUKAY Mert Gezek Cem Bülent Üstündağ
AbstractPatients may face challenges of taking medication in good order. Implantable, biodegradable drug delivery systems are useful options with minimum side effects in these cases. A lot of parameters can be adjusted in the systems. The two main components of the systems are the active ingredient and the polymeric support material which supports the active ingredient. Poly(lactic acid) (PLA) is one of the suitable polymers as a support material for many different aspects. In addition to this, PLA can be easily printed by 3D printers. Therefore, one of the most promising technologies that can be used with the implantable biodegradable drug delivery system is 3D printer technology. Aim of this study is to offer implantable and biodegradable PLA that would be placed on the skin beneath as a drug support material with tailoring morphological features that drug is loaded in different architectures for implantable drug delivery systems, especially controlled drug delivery by using a 3D modeling program that is SolidWorks, and Fused Deposition Modeling (FDM) technology for 3D printing. Some of models were printed.